Phase Problem

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Part of a series on Phase retrieval

See also

Single object phase retrieval

The phase problem

Many detectors are limited to measuring only the intensities of a wavefront, discarding the phase part. Unfortunately the phases contain valuable structural information, which is a problem for all coherent diffraction imaging (CDI) methods.

a 300
b 300

A cat and a bird, and their Fourier transforms.
Brightness = amplitude, color = phase. Idea from Cowtan (1).

A propagated wave (in the far field) is the Fourier transform of its source. Backpropagating a diffraction pattern is as simple as taking the inverse Fourier transform, but without the phases this is meaningless.

a 300
b 300

Inverse Fourier transforms when the phase part is changed.
a Amplitude from bird, phase from cat. b Amplitude from cat, phase from bird. The phases encode most of the structural information (1).

The phase problem is solved through a priori knowledge or assumptions about the sample (2). This knowledge acts as constraints for the inversion, forcing the solution to be unique.

Iterative phase retrieval

The first successful approach for phase retrieval came from Gerchberg and Saxton in 1972 (3), who used an iterative method to solve the phase problem for electron microscopy. Their method of optimizing in two different regimes each with its own restraints is still highly relevant to more modern phase retrieval schemes.

Gerchberg-Saxton algorithm and Fienup’s improvements

Maximum Likelihood Estimation

Fienup shows that the Gerchberg-Saxton algorithm is in essence solving an optimization problem for the error metric. However, this “loss function” is not strictly required to be the sum of squares. Another approach, based on probabilities, is known as Maximum Likelihood Estimation.

Difference Map and RAAR

References

1.
Cowtan, K. Picture Book of Fourier Transforms. (2001).
2.
Millane, R. P. Phase retrieval in crystallography and optics. Journal of the Optical Society of America A 7, 394 (1990).
3.
Gerchberg, R. W. & Saxton, W. O. A Practical Algorithm for the Determination of Phase from Image and Diffraction Plane Pictures. Optik 35, (1972).

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